I've used Graphene for a couple years now, and I have no complaints about it. Can't say how good it is compared to CalyxOS, since I've never used that. I like that it lets you enable/disable apps at will, control things like which apps have network/camera/etc permissions, and automatically disabling apps that you haven't used in a long time. It's a breath of fresh air compared to when all we had was Replicant OS shudders those were dark times indeed.